Microtubules interacting with a boundary: Mean length and mean first-passage times

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Microtubules interacting with a boundary: mean length and mean first-passage times.

I formulate a dynamical model for microtubules interacting with a catastrophe-inducing boundary. In this model microtubules are either waiting to be nucleated, actively growing or shrinking, or stalled at the boundary. I first determine the steady-state occupation of these various states and the resultant length distribution. Next, I formulate the problem of the mean first-passage time to reach...

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ژورنال

عنوان ژورنال: Physical Review E

سال: 2012

ISSN: 1539-3755,1550-2376

DOI: 10.1103/physreve.86.011902